{"id":5009,"date":"2021-10-11T16:05:06","date_gmt":"2021-10-11T13:05:06","guid":{"rendered":"https:\/\/dralexandrostraianos.gr\/?p=5009"},"modified":"2022-01-12T18:26:15","modified_gmt":"2022-01-12T16:26:15","slug":"%ce%bf%ce%be%ce%b5%ce%b9%ce%b4%cf%89%cf%84%ce%b9%ce%ba%cf%8c-%cf%83%cf%84%cf%81%ce%b5%cf%82-%ce%b7-%ce%ba%cf%8d%cf%81%ce%b9%ce%b1-%ce%b1%ce%b9%cf%84%ce%af%ce%b1-%ce%b2%ce%bb%ce%ac%ce%b2%ce%b7%cf%82","status":"publish","type":"post","link":"https:\/\/dralexandrostraianos.gr\/al\/%ce%bf%ce%be%ce%b5%ce%b9%ce%b4%cf%89%cf%84%ce%b9%ce%ba%cf%8c-%cf%83%cf%84%cf%81%ce%b5%cf%82-%ce%b7-%ce%ba%cf%8d%cf%81%ce%b9%ce%b1-%ce%b1%ce%b9%cf%84%ce%af%ce%b1-%ce%b2%ce%bb%ce%ac%ce%b2%ce%b7%cf%82\/","title":{"rendered":"STRESI OXIDATIV: SHKAQI KRYESOR I D\u00cbMTIMEVE T\u00cb ADN-s\u00eb s\u00eb Sperm\u00ebs"},"content":{"rendered":"

P\u00ebr 1 n\u00eb 6 \u00e7ifte q\u00eb kan\u00eb nevoj\u00eb p\u00ebr ndihm\u00eb p\u00ebr t\u00eb krijuar familje, faktor\u00ebt mashkullor\u00eb do t\u00eb jen\u00eb shkaku i problemeve t\u00eb infertilitetit deri n\u00eb 30%. Megjith\u00ebse nj\u00eb analiz\u00eb e p\u00ebrgjithshme e sperm\u00ebs mbetet "standardi i art\u00eb" p\u00ebr vler\u00ebsimin e cil\u00ebsis\u00eb s\u00eb sperm\u00ebs (kontrollimi i faktor\u00ebve si v\u00ebllimi, numri, l\u00ebvizshm\u00ebria, morfologjia dhe t\u00eb tjer\u00ebt), 25 - 40% t\u00eb rasteve t\u00eb infertilitetit mashkullor mund t\u00eb mbeten "t\u00eb pashpjegueshme" pas analiz\u00ebs s\u00eb sperm\u00ebs.<\/p>\n

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Nj\u00eb faktor q\u00eb mund t\u00eb shkaktoj\u00eb k\u00ebt\u00eb infertilitet "t\u00eb pashpjeguesh\u00ebm" \u00ebsht\u00eb stresi oksidativ. Nivelet e larta t\u00eb stresit oksidativ jan\u00eb lidhur me funksionin e dob\u00ebt t\u00eb sperm\u00ebs dhe d\u00ebmtimin e ADN-s\u00eb s\u00eb qelizave, duke rritur potencialisht rrezikun e rezultateve t\u00eb d\u00ebshtuara t\u00eb IVF. Por \u00e7far\u00eb \u00ebsht\u00eb stresi oksidativ dhe si ndikon ai n\u00eb fertilitetin mashkullor?<\/p>\n

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\u00c7far\u00eb \u00ebsht\u00eb stresi oksidativ?<\/strong><\/h3>\n

95% e oksigjenit q\u00eb hyn n\u00eb trupin ton\u00eb n\u00ebp\u00ebrmjet frym\u00ebmarrjes p\u00ebrdoret p\u00ebr prodhimin e energjis\u00eb, nd\u00ebrsa 5% e mbetur p\u00ebrdoret p\u00ebr prodhimin e radikaleve t\u00eb lira.<\/p>\n

Radikalet e lira n\u00eb sasi t\u00eb vogla jan\u00eb thelb\u00ebsore p\u00ebr sistemin ton\u00eb imunitar, nd\u00ebrsa kur p\u00ebrqendrimi i tyre rritet mbi normalen, ato mund t\u00eb shkaktojn\u00eb nj\u00eb s\u00ebr\u00eb problemesh, si d\u00ebmtime t\u00eb indeve, membranave qelizore dhe ADN-s\u00eb s\u00eb qelizave, p\u00ebrfshir\u00eb spermatozoidet. Ky quhet stres oksidativ.<\/p>\n

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Stresi oksidativ dhe fertiliteti mashkullor<\/strong><\/h3>\n

Nivelet e larta t\u00eb stresit oksidativ jan\u00eb lidhur me funksionin e dob\u00ebt t\u00eb sperm\u00ebs, rezultatet jonormale t\u00eb analiz\u00ebs s\u00eb sperm\u00ebs dhe rezultatet e d\u00ebshtuara t\u00eb IVF. Ka prova q\u00eb nivelet e larta t\u00eb stresit oksidativ mund t\u00eb shkaktojn\u00eb ndryshime n\u00eb membranat e sperm\u00ebs, duke ndikuar n\u00eb morfologjin\u00eb dhe l\u00ebvizshm\u00ebrin\u00eb e tyre, si dhe d\u00ebmtimin e ADN-s\u00eb s\u00eb tyre. Ky d\u00ebmtim i ADN-s\u00eb mund t\u00eb \u00e7oj\u00eb n\u00eb norma m\u00eb t\u00eb ul\u00ebta t\u00eb shtatz\u00ebnis\u00eb dhe nj\u00eb rrezik m\u00eb t\u00eb lart\u00eb t\u00eb abortit.<\/p>\n

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\u00c7far\u00eb e shkakton stresin oksidativ?<\/strong><\/h3>\n

Aft\u00ebsia jon\u00eb p\u00ebr t\u00eb prodhuar antioksidant\u00eb kontrollohet nga p\u00ebrb\u00ebrja jon\u00eb gjenetike dhe mund t\u00eb ndikohet nga m\u00ebnyra e jetes\u00ebs dhe dieta jon\u00eb. Prodhimi i radikaleve t\u00eb lira rritet nga shum\u00eb faktor\u00eb, duke p\u00ebrfshir\u00eb duhanin, alkoolin dhe nj\u00eb diet\u00eb me cil\u00ebsi t\u00eb dob\u00ebt t\u00eb lart\u00eb n\u00eb yndyrna t\u00eb ngopura, si dhe plakjen dhe mbipesh\u00ebn. Prodhimi i antioksidant\u00ebve n\u00eb trupin ton\u00eb duhet t\u00eb jet\u00eb i mjaftuesh\u00ebm p\u00ebr t\u00eb balancuar prodhimin e radikaleve t\u00eb lira, por p\u00ebr shum\u00eb njer\u00ebz mund t\u00eb ket\u00eb m\u00eb shum\u00eb radikale t\u00eb lira, duke \u00e7uar n\u00eb d\u00ebmtime t\u00eb qelizave dhe efekte afatgjata sh\u00ebndet\u00ebsore.<\/p>\n

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P\u00ebrballimi i niveleve t\u00eb larta t\u00eb stresit oksidativ<\/strong><\/h3>\n

Meqen\u00ebse sperma krijohet \u00e7do dit\u00eb, ju mund t\u00eb p\u00ebrmir\u00ebsoni cil\u00ebsin\u00eb e sperm\u00ebs n\u00eb vet\u00ebm tre muaj me modifikime t\u00eb thjeshta t\u00eb stilit t\u00eb jetes\u00ebs.<\/p>\n

\u00a0<\/strong><\/p>\n

Gj\u00ebja e r\u00ebnd\u00ebsishme p\u00ebr t\u00eb mbajtur mend \u00ebsht\u00eb se pasi t\u00eb kemi nj\u00eb diagnoz\u00eb t\u00eb stresit oksidativ t\u00eb sperm\u00ebs (ose ndonj\u00eb problem tjet\u00ebr t\u00eb infertilitetit mashkullor), ka shum\u00eb gj\u00ebra q\u00eb mund t\u00eb b\u00ebjm\u00eb p\u00ebr t'ju dh\u00ebn\u00eb shansin m\u00eb t\u00eb mir\u00eb p\u00ebr t\u00eb mbetur shtatz\u00ebn\u00eb.<\/strong><\/p>\n

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*P\u00ebrmbajtja n\u00eb k\u00ebt\u00eb blog nuk synon si z\u00ebvend\u00ebsim p\u00ebr k\u00ebshilla, diagnoz\u00eb ose trajtim profesional mjek\u00ebsor. Gjithmon\u00eb k\u00ebrkoni k\u00ebshill\u00ebn e ofruesve t\u00eb kualifikuar t\u00eb kujdesit sh\u00ebndet\u00ebsor p\u00ebr pyetjet q\u00eb mund t\u00eb keni n\u00eb lidhje me kushtet mjek\u00ebsore.<\/b><\/span><\/p>","protected":false},"excerpt":{"rendered":"

P\u00ebr 1 n\u00eb 6 \u00e7ifte q\u00eb kan\u00eb nevoj\u00eb p\u00ebr ndihm\u00eb p\u00ebr t\u00eb krijuar familje, faktor\u00ebt mashkullor\u00eb do t\u00eb jen\u00eb shkaku i deri n\u00eb 301% t\u00eb problemeve t\u00eb infertilitetit. Megjith\u00ebse nj\u00eb analiz\u00eb e p\u00ebrgjithshme e sperm\u00ebs mbetet "standardi i art\u00eb" p\u00ebr vler\u00ebsimin e cil\u00ebsis\u00eb s\u00eb sperm\u00ebs (kontrollimi i faktor\u00ebve t\u00eb till\u00eb si v\u00ebllimi, num\u00ebrimi, l\u00ebvizshm\u00ebria, morfologjia dhe m\u00eb shum\u00eb), 25 [\u2026]<\/p>","protected":false},"author":9,"featured_media":5012,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[376],"tags":[354,400,401],"class_list":["post-5009","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-376","tag-354","tag-400","tag-401"],"_links":{"self":[{"href":"https:\/\/dralexandrostraianos.gr\/al\/wp-json\/wp\/v2\/posts\/5009","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/dralexandrostraianos.gr\/al\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/dralexandrostraianos.gr\/al\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/dralexandrostraianos.gr\/al\/wp-json\/wp\/v2\/users\/9"}],"replies":[{"embeddable":true,"href":"https:\/\/dralexandrostraianos.gr\/al\/wp-json\/wp\/v2\/comments?post=5009"}],"version-history":[{"count":0,"href":"https:\/\/dralexandrostraianos.gr\/al\/wp-json\/wp\/v2\/posts\/5009\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/dralexandrostraianos.gr\/al\/wp-json\/wp\/v2\/media\/5012"}],"wp:attachment":[{"href":"https:\/\/dralexandrostraianos.gr\/al\/wp-json\/wp\/v2\/media?parent=5009"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/dralexandrostraianos.gr\/al\/wp-json\/wp\/v2\/categories?post=5009"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/dralexandrostraianos.gr\/al\/wp-json\/wp\/v2\/tags?post=5009"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}