Center for Reproductive and Fetal Medicine

WHAT YOU NEED TO KNOW ABOUT PRE-ECLAMPSIA

WHAT YOU NEED TO KNOW ABOUT PRE-ECLAMPSIA

What is pre-eclampsia?

Preeclampsia is a serious medical condition that develops during pregnancy. Women with preeclampsia often have high blood pressure (hypertension) and high levels of protein in their urine (proteinuria). Preeclampsia usually develops after the 20th week of pregnancy. It can also affect other organs in the body and be dangerous for both the mother and the developing fetus. Because of these risks, preeclampsia must be treated promptly by a health care provider.

What happens in preeclampsia?

When you have pre-eclampsia, your blood pressure rises (above 140/90 mmHg) and you may have high levels of protein in your urine. Preeclampsia puts pressure on the heart and other organs and can cause serious complications. It can also affect the blood supply to the placenta, affect liver and kidney function, or cause fluid to build up in the lungs. Protein in the urine is a sign of kidney dysfunction.

How common is preeclampsia?

Preeclampsia is a condition that occurs during pregnancy and complicates up to 8% of all deliveries worldwide. 

Who can get preeclampsia?

Preeclampsia tends to be more common in early pregnancies. However, it is not clear why some women develop preeclampsia. Some factors that may put you at higher risk are:

  • History of high blood pressure, kidney disease or diabetes
  • Multiple Pregnancy
  • Family history of preeclampsia
  • Autoimmune Diseases
  • Obesity

 

What are the symptoms?

Many women with preeclampsia have no symptoms. For those who do, some of the first signs of preeclampsia are high blood pressure, protein in the urine, and fluid retention (this can cause weight gain and swelling). Other signs of preeclampsia include:

  • Headaches
  • Blurred vision or sensitivity to light
  • Appearance of dark spots in your vision
  • Abdominal pain on the right side
  • Swelling of the hands and face (edema)
  • Breathing difficulty

 

It is essential to share all your pregnancy symptoms with your gynecologist. Many women don't know they have preeclampsia until they have their blood pressure and/or urine checked at an antenatal appointment. Severe preeclampsia can include symptoms such as:

  • Hypertensive emergency (blood pressure is 160/110 mmHg or higher)
  • Reduced kidney or liver function
  • Fluid in the lungs
  • Low levels of platelets in the blood (thrombocytopenia)
  • Decreased urine output

 

If your preeclampsia is severe, you may be admitted to hospital for closer monitoring or you may need to deliver your baby as soon as possible. Your obstetrician may give you medicine for high blood pressure or to help the fetus's lungs develop before delivery.

What causes preeclampsia?

As mentioned, there is currently no official cause for the development of preeclampsia. It is believed, however, to come from a problem with the placenta (the organ that develops in the womb during pregnancy and is responsible for delivering oxygen and nutrients to the fetus). The blood supply to the placenta can be reduced in preeclampsia and this can lead to problems for both the pregnant woman and the fetus.

Can stress cause pre-eclampsia?

While stress can affect blood pressure, it is not one of the direct causes of preeclampsia. While some stress is inevitable during pregnancy, it's a good idea to avoid high-stress situations or develop stress management techniques.

What week of pregnancy does preeclampsia start?

Preeclampsia usually occurs after 20 weeks of pregnancy, but can occur earlier. Most preeclampsia occurs near 37 weeks of gestation. Preeclampsia can also occur after giving birth (postpartum preeclampsia), which usually occurs between the first few days and one week after delivery. In rare cases, it starts weeks after giving birth.

Will preeclampsia affect my baby?

Preeclampsia can cause premature labor. Premature babies are at increased risk for health complications such as low birth weight and breathing problems.

How is the diagnosis made?

Preeclampsia is often diagnosed during routine prenatal appointments when the gynecologist checks weight gain, blood pressure and urine. If preeclampsia is suspected, your healthcare provider may: → Write additional blood tests to check kidney and liver function. → Suggest a 24-hour urine collection to monitor proteinuria. → Perform ultrasound and other monitoring of the fetus to see the size of the fetus and assess the volume of amniotic fluid. Preeclampsia can be categorized as mild or severe. You may be diagnosed with mild preeclampsia if you have high blood pressure plus high levels of protein in your urine. You are diagnosed with severe preeclampsia if you have symptoms of mild preeclampsia plus:

  • Signs of kidney or liver damage (shown in blood test)
  • Low platelet count
  • Fluid in the lungs
  • Headaches and dizziness
  • Impairment of vision or appearance of spots

 

How is preeclampsia treated?

Your gynecologist will advise you on the best way to treat preeclampsia. Treatment generally depends on how severe the preeclampsia is and how far along you are in the pregnancy. If you are close to full (37 weeks pregnant or more), your baby will likely be born early. You can still have a vaginal birth, but sometimes a C-section is recommended. Your health care provider may give you medicine to help the fetus's lungs grow and to manage your blood pressure until the baby is born. Sometimes it is safer to deliver the baby early than to risk prolonging the pregnancy. When preeclampsia develops earlier in pregnancy, you will be closely monitored in an attempt to prolong the pregnancy and allow the fetus to grow. You will have more prenatal appointments, including ultrasounds, urine tests, and blood tests. You may be asked to check your blood pressure at home. If you are diagnosed with severe preeclampsia, you could stay in hospital until you deliver your baby. If preeclampsia worsens or becomes more severe, your baby will need to be delivered. During labor and after birth, people with preeclampsia are often given magnesium intravenously to prevent the development of eclampsia (seizures from preeclampsia).

Is there a cure for preeclampsia?

No, there is no official treatment for preeclampsia. Pre-eclampsia can only be treated by delivery. Your healthcare provider will still want to monitor you for several weeks after delivery to make sure your symptoms go away.

Prevention- How can I reduce my risk of getting preeclampsia?

For people with risk factors, there are some steps that can be taken before and during pregnancy to reduce the chance of developing preeclampsia. These steps may include:

  • Weight loss if you are overweight/obese (before pregnancy-related weight gain)
  • Checking your blood pressure and blood sugar (if you had high blood pressure or diabetes before pregnancy).
  • Maintaining a regular exercise routine
  • Adequate sleep
  • Eating healthy foods with low salt content and avoiding caffeine

 

What are the most common complications of preeclampsia?

If left untreated, preeclampsia can be potentially fatal to both you and the fetus. Before delivery, the most common complications are premature delivery, low birth weight or placental abruption. Pre-eclampsia can cause HELLP syndrome (hemolysis, elevated liver enzymes and low platelet count). This happens when preeclampsia damages the liver and red blood cells and interferes with blood clotting. Other signs of HELLP syndrome are blurred vision, chest pain, headaches and nosebleeds. After you give birth to your baby, you may be at increased risk for:

  • Kidney disease
  • Heart attack
  • Stroke
  • Development of preeclampsia in future pregnancies

 

Does pre-eclampsia go away after delivery?

Preeclampsia usually resolves within days to weeks after delivery. Sometimes, your blood pressure may remain high for a few weeks after giving birth, requiring drug treatment. Your healthcare provider will work with you after your pregnancy to manage your blood pressure. People with preeclampsia – particularly those who develop the condition early in pregnancy – are at greater risk for high blood pressure (hypertension) and heart disease later in life. Knowing this information, these individuals can work with their primary care provider to take steps to reduce these risks.

What is postpartum preeclampsia?

Postpartum preeclampsia is when you develop preeclampsia after your baby is born. It usually occurs within two days of giving birth, but it can also develop several weeks later. The signs of postpartum preeclampsia are similar to preeclampsia and include swelling in the extremities, headaches, spotting, stomach pain, and nausea. It is a serious condition that can cause seizures, stroke and organ damage.

What is the difference between preeclampsia and eclampsia?

Eclampsia is severe pre-eclampsia that causes seizures. It is considered a complication of preeclampsia, but can occur without signs of preeclampsia. In rare cases, it can lead to coma, stroke or death.

summarizing

Pre-eclampsia is a serious condition that you may not even know you have. It's important to be consistent with all your prenatal appointments and be open about any symptoms you feel during pregnancy. When preeclampsia is diagnosed early, it can be treated and keep both you and the fetus safe and healthy. Most women with preeclampsia go on to have healthy babies.

Center for Reproductive and Fetal Medicine

Effective doctor-patient communication is vital to providing high-quality health care. Any communication regarding your medical profile (getting results, instructions, answering questions, concerns) will be done directly with the doctor. This means no midwife or secretary will interrupt your conversations. Instead, if you call with any concerns, they will be there right away to address your needs. Contact us by calling 694 649 8771 or by completing the relevant Contact Form.

Dr. Alexandros Traianos

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REPRODUCTIVE MEDICINE

FREQUENT QUESTIONS

The association of IVF drugs with cancer risk is a major concern for women enrolled in these programs. But the plethora of bibliographic reports collected from credible scientific studies and published in reputable medical journals worldwide are reassuring and do not confirm this concern.

Of course not. In about a third of cases, infertility is due to the woman (female factor), while in a third of cases, it is due to the man (male factor). The remaining one-third is due to both (both men and women) or even to unknown factors.

The quantity and quality of a man's sperm can be affected by his health and lifestyle. Some factors that can reduce the quantity and / or quality of sperm are:

  • the alcohol
  • drugs
  • environmental toxins, including pesticides and lead
  • smoking
  • health problems
  • medicines
  • radiotherapy and chemotherapy
  • the age

Success rates vary at each IVF Center. Very important factors are also the age of the woman, the levels of her hormones and of course the sperm of the husband. Rates generally range from 45% or slightly higher for women up to 35 years old.

Infertility is defined as the failure to conceive after one year (or 6 months, if it is a woman over 35) with normal, regular sexual intercourse. In other words, when a year passes without the woman becoming pregnant, the couple should consult their doctor to determine the cause of the pregnancy and then treat it. We must all, however, be aware and not forget that the age factor is the most critical for female fertility and that the individualized approach of each couple is the "golden key" that solves the problem.

The number of treatment cycles a woman can undergo is not specified. It is certain that in our country there are high level obstetricians-gynecologists and organized infertility treatment centers, which offer impeccable medical services at this level. If there are correct indications (eg ovaries that respond to stimulation therapy, good quality endometrium, etc.) the success rate -especially with the use of newer techniques and biotechnological drugs, which show increased bioactivity compared to conventional drugs from urine- totals approximately 65%-70% after 4 cycles of treatment.

At the Center for Reproductive Medicine of Dr. Traianos we offer egg / sperm cryopreservation services for those who have a personal or medical reason and need this service. We use the most modern vitrification technique in the freezing of sperm and eggs.

The collection of eggs takes 10-15 minutes, it is not painful, it is done under intoxication and after the end of the process you return to your activities.

In general, experts agree that the fact that a couple has already had a child can be considered proof that there is no infertility problem in the first place. It is like a small test that has been done and proves that they "made it" at least once. On the other hand, however, we must be aware that things may have changed in the meantime and a problem may have arisen (e.g. the man may have suffered some inflammation, which affects the quality of his sperm or something has intervened that affects female fertility: an inflammation, a gynecological surgery, an abortion, etc.).

In any case, if a reasonable period of time (one year) passes and a couple is unable to achieve pregnancy, then they should, with the help of their doctor, investigate whether there has been a problem causing infertility.