Center for Reproductive and Fetal Medicine

Endometriosis and obstetric complications

Endometriosis and obstetric complications

Endometriosis and obstetric complications

Doctors suggest ways to reduce obstetric complications in women with endometriosis

THE endometriosis is a pathological process accompanied by development benign tissues (which are morphologically and functionally similar to the endometrium) outside the uterine cavity. In premenstrual phase, the endometrium it becomes thicker and if the egg is not fertilized, it is removed from the uterine cavity with the menstrual cells. This procedure is almost painless in healthy women, but in patients with endometriosis, is accompanied by inflammation of the surrounding tissues.

Such patients suffer from chronic pelvic pain, menstrual cramps, painful intercourse and often infertility. 10% to 15% of women of childbearing age have endometriosis and 30% to 40% display complications at birth.

A team of doctors from RUDN University with their Italian colleagues had studied the data of existing studies on with the effect of endometriosis on pregnancy and childbirth and suggested ways to reduce obstetric complications in women with this condition. The results of the study were published in The Journal of Maternal-Fetal & Neonatal Medicine.

Despite the prevalence of endometriosis, the plans for obstetric complications have not yet been properly studied. The team of doctors from RUDN University with their Italian colleagues studied the data of previous works and suggested ways to prevent obstetric complications in women with this condition.

 "Previous studies have focused on biological factors that affect the course of pregnancy in women with endometriosis. We know that thePatients with endometriosis may experience miscarriages, premature birth or other complications due to immune and endocrine disorders in the uterus. However, the mechanism of obstetric complications is still an unclear issue. That's why we made one systematic review of the literature and we studied the effects of endometriosis on pregnancy taking into account factors such as the method of treatment and conception, as well as the stage and location of the pathological process. We also suggested ways to prevent obstetric complications in patients with a history of endometriosis. ” said one of the researchers.

The team analyzed the results of previous studies, taking into account any possible complications: premature birth, hypertensive complications during pregnancy, placental abnormalities, risk of cesarean section, degraded fetus and stillbirth. Based on the results of the study, the team suggested various methods to improve the prognosis of pregnancy.

That is, the laparoscopy was mentioned as the main treatment option in case of attachment. Laparoscopy is one modern surgical method allowing doctors to destroy the adhesions between peritoneal and pelvic organs using special endoscopic devices. This helps combating infertility and reduces discomfort and pain in patients with endometriosis.

According to the team, methods of conception should be chosen based on the stages of the disease. Recommended for patients with advanced stages of endometriosis to undergo hormone therapy and women after surgery - in vitro fertilization by embryo transfer (IVF / ET). The team had suggested that all patients be diagnosed endometriosis should start taking 400 micrograms of folic acid before conception to reduce the risk of preterm birth.

"The results of different studies are controversial: some of them did not take into account the simultaneous hormone treatment and some had methodological limitations. However, we have been able to develop a fairly clear picture of all possible obstetric complications in patients with endometriosis, to establish causal relationships and identify issues for further discussion, ”concluded the head of the investigation.

* The content on this blog is not intended to replace professional medical advice, diagnosis or treatment. Always seek the advice of qualified health care providers with questions you may have about medical conditions.

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Dr. Alexandros Traianos

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FREQUENT QUESTIONS

The association of IVF drugs with cancer risk is a major concern for women enrolled in these programs. But the plethora of bibliographic reports collected from credible scientific studies and published in reputable medical journals worldwide are reassuring and do not confirm this concern.

Of course not. In about a third of cases, infertility is due to the woman (female factor), while in a third of cases, it is due to the man (male factor). The remaining one-third is due to both (both men and women) or even to unknown factors.

The quantity and quality of a man's sperm can be affected by his health and lifestyle. Some factors that can reduce the quantity and / or quality of sperm are:

  • the alcohol
  • drugs
  • environmental toxins, including pesticides and lead
  • smoking
  • health problems
  • medicines
  • radiotherapy and chemotherapy
  • the age

Success rates vary at each IVF Center. Very important factors are also the age of the woman, the levels of her hormones and of course the sperm of the husband. Rates generally range from 45% or slightly higher for women up to 35 years old.

Infertility is defined as the failure to conceive after one year (or 6 months, if it is a woman over 35) with normal, regular sexual intercourse. In other words, when a year passes without the woman becoming pregnant, the couple should consult their doctor to determine the cause of the pregnancy and then treat it. We must all, however, be aware and not forget that the age factor is the most critical for female fertility and that the individualized approach of each couple is the "golden key" that solves the problem.

The number of treatment cycles a woman can undergo is not specified. It is certain that in our country there are high level obstetricians-gynecologists and organized infertility treatment centers, which offer impeccable medical services at this level. If there are correct indications (eg ovaries that respond to stimulation therapy, good quality endometrium, etc.) the success rate -especially with the use of newer techniques and biotechnological drugs, which show increased bioactivity compared to conventional drugs from urine- totals approximately 65%-70% after 4 cycles of treatment.

At the Center for Reproductive Medicine of Dr. Traianos we offer egg / sperm cryopreservation services for those who have a personal or medical reason and need this service. We use the most modern vitrification technique in the freezing of sperm and eggs.

The collection of eggs takes 10-15 minutes, it is not painful, it is done under intoxication and after the end of the process you return to your activities.

In general, experts agree that the fact that a couple has already had a child can be considered evidence that there is no infertility problem in the first place. It is like a small test that has been done and proves that they "succeeded" at least once. On the other hand, we need to know that in the meantime things may have changed and a problem may have arisen (eg the man may have had some inflammation that affects the quality of his sperm or has mediated something that affects female fertility: an inflammation, a gynecological surgery, an abortion, etc.). In any case, if a reasonable period of time (one year) passes and a couple can not achieve a pregnancy, then he should with the help of his doctor investigate if there has been a problem that causes infertility.