Any diagnosis of infertility can be difficult to treat - but when all the usual blood tests are normal and every diagnosis, sample and test reveals nothing remarkable - then we are talking about unexplained infertility.
Infertility can be described as "unexplained" if a woman ovulates regularly, her fallopian tubes are OK, there is no sign of endometriosis or adhesions, and if the man has a normal sperm count. If the couple has sex at least twice a week during the ovulation period, but there is no conception after two 12 months, then a diagnosis of unexplained infertility may be appropriate.
Fertility tests should include a vaginal ultrasound to check for ovarian abnormalities, blood tests to check for egg release, and a sperm test.
If one or both of you smoke, are overweight or have a medical condition that is not well controlled, fertility tests may be all normal, but the pregnancy attempt may not be successful. With a detailed review of your personal and medical history, a Reproductive Medicine Specialist may be able to identify something that needs to change to help you achieve a pregnancy.
Some women may release eggs before they mature or their eggs may have chromosomal abnormalities - especially if the woman is older or is experiencing premature menopause. If there is a suspicion of an egg quality or quantity problem, further tests are indicated.
For men, while a simple sperm analysis can show that there is enough sperm to move normally, it does not reveal if the sperm is healthy. An additional test that detects if you have high levels of damage to sperm DNA can help you understand why a pregnancy has not yet been achieved.
What not all tests can tell us is whether the sperm fertilizes the egg and unfortunately this can only be assessed during the IVF treatment itself. However, if this happens, there are treatments available that can address this issue.
There are many reasons for infertility and those mentioned above are some of the most common. If you have been trying to conceive for a long time without success, the best advice is to seek help early. At the "Alexandros Traianos" Center for Reproductive Medicine & Fetal Medicine we see many patients who do not have a clear reason why they have not had a pregnancy - but their treatment can be successful even if infertility remains unexplained.
* The content on this blog is not intended to replace professional medical advice, diagnosis or treatment. Always seek the advice of qualified health care providers with questions you may have about medical conditions.