From December 2019, the manifestation of his disease coronavirus (COVID-19), which originated in Wuhan, China, has become a global threat to public health. On February 28, 2020, the WHO upgraded its assessment of its risk of spread and risk of impact COVID-19 at a very high level globally. THE epidemic has spread in 118 countries around the world.
With immunosuppressed state and normal adaptive changes during pregnancy, pregnant women could be more susceptible to infection than COVID-19 than the general population. As the virus spreads rapidly, the parent management and fetal safety are a major concern, but there is little evaluation and management information pregnant women infected with COVID-19 and the potential risk of vertical transmission is unclear. In The Lancet Infectious Diseases, they report its clinical features and obstetric and neonatal results pregnancy with COVID-19 pneumonia in Wuhan, China. Seven women were examined you were pregnant with pneumonia COVID-19 and onset symptoms it was similar with those reported in non-pregnant adults with COVID-19. All patients received oxygen therapy and antiviral therapy in isolation. All patients did caesarean section section after consultation with a multidisciplinary team and the results of pregnant women and newborns were good. Three newborns were tested for severe acute respiratory syndrome (SARS-CoV-2) and were found to be infected with COVID-19 36 hours after birth. The findings of the study provide some indications for clinical evaluation and management of pregnant women with COVID-19, but questions remain about how to treat infected pregnant women.
As reported, five pregnant women took steroids after cesarean. Two are also treated with traditional Chinese medicine. However, no reliable evidence is specific COVID-19 treatment for pregnant women. The guidance of the WHO and some clinical data do not recommend the use of corticosteroids for COVID-19. THE use of drugs in pregnant women should be based on solid data.
Are required clinical tests to demonstrate the effectiveness of drugs and effects on the fetus to create a standard treatment ca pregnant woman with COVID-19.
Previous treatment experience did not come to the conclusion on which method of administration is safest in this patient population. Scientists reported nine pregnant women with COVID-19. Seven of the women gave birth to their babies with cesarean and two with vaginal delivery. All three newborns born by vaginal delivery(including two who were twins) had an Apgar score of at least 9 and anegative nucleic acid test for SARS-CoV-2.
According to the study, while all mothers and infants showed good results, women were in the third trimester and had only mild symptoms. Hence the effect of infection SARS-CoV-2 in the fetus during the first or second trimester or in patients with moderate to severe infection remains to be investigated. Further research is required for risk assessment and for drawing up guidelines for delivery times and methods in patients with COVID-19.
According to a previous study, SARS virus infection during pregnancy can cause premature birth. In the study three newborns tested for SARS-CoV-2, two of which were negative. One newborn was positive, but the placental viral nucleic acid and umbilical cord blood tests were negative in this case. At the end of follow-up, no pneumonia or other clinical symptoms and signs were reported in any of these seven neonates. There is no reliable evidence to support the possibility of vertical transmission of COVID-19 infection from mother to baby. The results are in line with previous reports.
But all these studies evaluated only a small number of cases. Future studies should include a larger number of sampling at multiple centers in order to determine if there may be vertical transmission between mother and newborn.
However, understanding it SARS-CoV-2, especially the effect in pregnant women and newborns, is still insufficient. Research needs to be further strengthened to provide a sound basis for medical management for pregnant patients with COVID-19.
* The content on this blog is not intended to replace professional medical advice, diagnosis or treatment. Always seek the advice of qualified health care providers with questions you may have about medical conditions.
